Respiratory Syncytial Virus (RSV) is responsible for many chronic conditions such as pneumonia, bronchitis, asthma, and respiratory disease. It primarily affects neonates, infants and adults and is responsible for outpatient visits, hospitalization and death in some cases. Therefore, diagnosis of RSV- associated diseases is crucial to avoid further medical severity. Symptoms of RSV presence include, rhinorrhea, cough, wheeze, respiratory distress, and hypoxemia. Molecular diagnostic is most widely used techniques for diagnosing RSV.

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According to a report by the Lancet, 2017, around 33·1 million episodes of RSV induced acute lower respiratory infections that resulted in around 3·2 million hospitalizations and around 59,600 in-hospital deaths in children younger than 5 years of age, worldwide, in 2015. Moreover, the report stated that the overall RSV- acute lower respiratory infections- related mortality was around 118200 in 2015.

Furthermore, high prevalence of several chronic conditions such as pneumonia and other respiratory tract infections due to RSV is a major factor contributing to growth of the market over the forecast period. For instance, according to a report by World Health Organization (WHO), May 2018, chronic obstructive pulmonary disease (COPD) and lower respiratory tract infection are amongst top five chronic diseases with highest mortality rate, worldwide. The report stated that around 3 million each deaths were registered due to COPD and lower respiratory tract infection in 2016, worldwide.

On the basis of Geography, respiratory syncytial virus diagnostics market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to be dominant in the respiratory syncytial virus diagnostics market over the forecast period.

According to study published in journal American Family Physician in 2017, around 2% to 3% of infants, younger than 12 months are hospitalized with an RSV infection, annually, in the U.S. As per same source, Around 57,500 hospitalizations and 2.1 million outpatient visits are associated with RSV infections in children younger than five years, annually, in the U.S. It can be concluded from epidemiological data that the U.S. has high potential for respiratory syncytial virus diagnostics market. Presence of key players and their products in North America would be another important driver for the market growth.

Asia Pacific and Latin America would witness highest CAGR in respiratory syncytial virus diagnostics market. According to study published in the Lancet in September 2017, lower middle income countries witnessed around 43,600 deaths due to RSV-ALRI whereas upper middle income countries witnessed around 17900 deaths, in 2015. Furthermore, children in this region often do not receive adequate vaccination, which leads to frequent infection incidences from variety of diseases including RSV. According to World Health Organization (WHO) 2018, worldwide, around 86% of infants are vaccinated against 26 diseases. However, around 19.5 million children remain unvaccinated that leads to around 2-3 million deaths, annually, of which around 90% belong to low and middle income countries.

WHO is running the pilot projects of vaccination in countries of developing regions such Latin America, Africa, and Asia Pacific to achieve100% detection of the RSV infections amongst infants, neonates and children under five years of age.This is expected to reduce the mortality rate and hospitalization from RSV associated acute lower respiratory infections (ALRI). It would also establish RSV diagnostic centers over the forecast period in these regions.

Chronic lymphocytic leukemia (CLL) is a most common type of leukemia found in adults. It is a kind of malignancy characterized by production of abnormal white blood cells in the bone marrow. Symptoms include, swelling of the lymph nodes, fatigue, fever, infection, pain beneath the ribs, and weight loss. Although CLL is rarely seen in children and people under age 40, it is more prevalent in geriatric population. Moreover, causes of CLL are largely unknown and it is more severe than acute leukemia. The prevalence of CLL is high in males than females. Although, the incidence of this disorder is higher in white population than Asian populations, the precise cause for this cannot be explained.

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The diagnosis of CLL includes Blood Cell Count and Examination, Bone Marrow Examination for patients followed by treatment. The treatment includes single or combination drug therapy, targeted therapies, monoclonal antibody therapies, white blood cell (neutrophil) growth factors. In addition to this, there are radiation therapy and splenectomy which are rarely used for the treatment.

According to the American Cancer Society (ACS) estimates, around 20,110 new cases of chronic lymphocytic leukemia and 4,660 deaths from CLL is expected in year 2017 in U.S. Furthermore, high prevalence of CLL in geriatric population is expected to increase demand for chronic lymphocytic leukemia therapeutics. According to the United Nations data, in 2015, around 901 million people in the world were over 60 years of age and this number is expected to reach 1.4 billion by 2030 and to 2.1 billion by 2050.

Furthermore, increasing number of incidences of comorbidities, especially among geriatric population and launch of new pipeline drugs are major factors contributing to growth of the chronic lymphocytic leukemia therapeutics market. For instance, on December 8, 2015, Bendeka injection—manufactured under the collaboration of Teva Pharmaceuticals Industries Ltd. and Eagle Pharmaceuticals Inc. acquired approval from FDA for the treatment of patients with CLL and indolent B-cell non-Hodgkin lymphoma (NHL) — progressed during or within six months of treatment with rituximab or a rituximab-containing regimen.

On the basis of region, the chronic lymphocytic leukemia therapeutics market is segmented into North America, Europe, Latin America, Asia Pacific, Middle East, and Africa. North America accounted for the largest market share in 2016 due to the presence of breakthrough pipeline drugs. For instance, the drug Acalabrutinib—manufactured by Acerta Pharma BV—is under phase 2 clinical trial for the treatment of CLL and small lymphocytic lymphoma (SLL) and the study is expected to complete in January 2019

H1N1 influenza virus causes viral disease, commonly known as swine flu, which mostly affects the respiratory system. Swine flu is characterized by infection from H1N1 strain. Symptoms of H1N1 flu are fever, cough, sore throat, runny or stuffy nose, watery and red eyes, body aches, headache, fatigue, and diarrhea. H1N1 spreads through contact with contaminated air or geographical locations infected with virus. H1N1 infection may worsen other chronic respiratory conditions such as bronchitis, pneumonia, COPD, and sometimes even death due to respiratory failure.

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H1N1 vaccine is an important innovation to tackle the H1N1 pandemic since 2009. Initially, the vaccines developed or available were inactivated monovalent vaccines that could prevent infection from most of the strains of H1N1. There are two routes of administration such as intradermal for inactivated vaccine and intranasal for live attenuated vaccine. Both routes shown efficacy profile and are bioequivalent against preventing H1N1 infection. Global H1N1 vaccine market has presence of both multinational pharmaceutical companies and companies from emerging economies.

One of the major factor propelling growth of H1N1 market is increased incidence of disease and episodes of pandemic worldwide from H1N1 infection. According to World Health Organization’s (WHO) 2018, factsheet estimates, 290,000 to 650,000 deaths are reported each year from all types of influenza infection (including Influenza A i.e. H1N1). Each year there are 3 to 5 million cases of severe illness from viral influenza infection globally, according to the same source.

Government initiatives, both internationally and nationally, to tackle H1N1 pandemic would positively impact the market growth. Health institution such as World Health Organization (WHO) have been instrumental in developing vaccines and supporting efficient distribution of the vaccine. After 2009 pandemic of H1N1 influenza, the U.S. government initiated US$ 3 billion H1N1 vaccine project under which it contracted five major companies to develop vaccine for H1N1 influenza. Under the WHO’s Global Influenza Surveillance and Response System, National Influenza Centers and WHO Collaborating Centers are continuously monitoring the influenza viruses circulating in humans and updates the composition of influenza vaccines twice a year.

Global population is crossing the age of 60 at annual rate of 3% according to 2017 UN report. Increased age, maximizes the risk of various respiratory tract related diseases and immune deficient diseases, thereby the risk for infection due to H1N1 virus rises. Awareness amongst patients about preventive healthcare approaches such as vaccination may lead to higher demand for H1N1 vaccines during forecast period.

However, seasonal nature of occurrence of H1N1 flu has led to meagre revenue for many of the key players. For instance, India-based Serum Institute, which produces intranasal live vaccine to treat swine flu had to destroy stock of 2 million doses in the year 2011 due to lack of demand. In contrast, if pandemic arises suddenly, supply of vaccine may be delayed due to slow production of vaccine, which may negatively affect health of many patients. Due to constant evolving nature of H1N1 virus, vaccine may prove to be ineffective in some parts of the world, which may deter the use of vaccines.

Angioplasty balloon is a medical device that is used for surgical widening or unblocking of a blood vessel, especially a coronary artery. A noticeable increase in health conditions have been is observed due to some factors that cause heart related diseases such as obesity, poor diet, and extra cholesterol. .Coronary artery disease is a life threatening disease which occurs due to insufficient supply of blood to the heart, leading to cardiac arrest. Thus, a person experiencing such medical condition should be treated with angioplasty procedure, which cleans the narrow and blocked blood veins. Angioplasty includes insertion of a small balloon tipped catheter into the blood vessel, which is then inflated at the site of blockage to help open the narrowed arteries.

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According to the health protection agency survey 2016, around 610,000 people die every year in the U.S. due to heart defects and this number is still on an upsurge. According to World Health Organizations (WHO) 2011, around 8 million individuals suffering from peripheral artery disease were recorded in the U.S. Coronary heart disease is a major cause of all the deaths in the country, which accounted for around 45% of total deaths. The prevalence of these diseases are expected to increase over the forecast period. Moreover, the growing ageing population experiencing heart ailments and diabetes, is expected to create higher demand angioplasty balloon catheters over the forecast period.

Increasing number of cardiovascular disease such as peripheral disease, coronary heart disease, and diabetes increase the global market value of angioplasty balloon. However, increase in number of key players of angioplasty balloon market has resulted in price conflicts, which is expected to curb growth of the global market.

Rise in the demand for angioplasty balloon in North America, makes it a global leader.

According to world health organizations (WHO) 2014, the North America angioplasty balloon market is predicted to reach 38% of global market share during next decade. According to the same reports, around 3.4 million people in North America are suffering from cardiovascular diseases. The growing healthcare facilities involving angioplasty in this region, have contributed to market growth. Moreover, the North American region is also a center of technological advancements and inventions of new products for catheters and angioplasty balloon, which further helps boost the market for angioplasty balloon. This makes North America a global leader of angioplasty balloon market.

According to the World Health Organizations reports (WHO) 2016, European region was the second leading global market for angioplasty balloon usage, due to the presence of large geriatric population suffering from cardiovascular diseases in the region. However, Asia Pacific region is expected to lead and emerge as the leading global user for angioplasty balloon over the forecast period. This is due to the world’s largest population present in this region with a noticeable number of people suffering from heart diseases. The costs of angioplasty balloon has decreased by around 40% in over recent decade in India, Japan, and China, which is significantly indicates growth of the angioplasty balloon market in Asia-Pacific.